L-R: Drs. Pina Colorusso, Lucy Swift, Craig Brideau
July 4, 2023
A Biologist’s Guide to Planning and Performing Quantitative Bioimaging Experiments
As biologists are adopting quantitative bioimaging, and these experiments become more complex, researchers need additional expertise to carry out their work in a rigorous and reproducible manner
Technological advancements in biology and microscopy have empowered a transition from bioimaging as an observational method to a quantitative one. However, as biologists are adopting quantitative bioimaging and these experiments become more complex, researchers need additional expertise to carry out this work in a rigorous and reproducible manner.
A recent essay published in PLOS Biology by a team of researchers including Snyder Institute members Dr. Pina Colarusso, PhD, Dr. Lucy Swift, PhD, and Dr. Craig Brideau, PhD, provides a navigational guide for experimental biologists to aid understanding of quantitative bioimaging from sample preparation through to image acquisition, image analysis, and data interpretation.
The essay includes a discussion of the interconnectedness of these steps, and for each, the team provides general recommendations, key questions to consider, and links to high-quality open-access resources for further learning. This synthesis of information will empower biologists to plan and execute rigorous quantitative bioimaging experiments efficiently. Read more.